Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH61455.1KEGG: tpd:Teth39_0567 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein. (414 aa)    
Predicted Functional Partners:
ADH61456.1
TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; KEGG: tpd:Teth39_0566 carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family.
  
  
 0.861
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.764
comB
PFAM: 2-phosphosulfolactate phosphatase; KEGG: tpd:Teth39_0568 2-phosphosulfolactate phosphatase; Belongs to the ComB family.
       0.760
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
  
 0.721
ADH61458.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
  
  
 0.698
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.687
ADH61126.1
KEGG: tpd:Teth39_0898 hypothetical protein.
  
     0.678
ADH61450.1
PFAM: cell cycle protein; KEGG: tpd:Teth39_0572 cell cycle protein; Belongs to the SEDS family.
  
    0.673
ADH61457.1
PFAM: Peptidase M23; KEGG: tpd:Teth39_0565 peptidase M23B.
       0.667
ADH61451.1
KEGG: tpd:Teth39_0571 FHA domain-containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
       0.664
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (26%) [HD]