Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61676.1TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: tpd:Teth39_0321 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (166 aa)    
Predicted Functional Partners:
ADH61677.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
TIGRFAM: GTP cyclohydrolase I; KEGG: tpd:Teth39_0319 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
 0.999
ADH61367.1
KEGG: tex:Teth514_1129 beta-lactamase domain-containing protein.
     
  0.900
ADH61693.1
KEGG: tpd:Teth39_0304 hypothetical protein.
  
  
 0.874
ADH61675.1
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tpd:Teth39_0322 putative 6-pyruvoyl tetrahydropterin synthase.
     
 0.857
ADH61228.1
PFAM: protein of unknown function DUF523; KEGG: tpd:Teth39_0776 hypothetical protein.
 
      0.856
sfsA
KEGG: tpd:Teth39_0323 sugar fermentation stimulation protein A; TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; Belongs to the SfsA family.
       0.783
ADH59825.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.749
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.736
ADH60527.1
KEGG: tpd:Teth39_1528 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; Belongs to the folylpolyglutamate synthase family.
  
  
 0.697
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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