Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH61692.1PFAM: carboxyl transferase; KEGG: tpd:Teth39_0305 carboxyl transferase. (516 aa)    
Predicted Functional Partners:
ADH61690.1
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: tpd:Teth39_0307 biotin/lipoyl attachment domain-containing protein.
 
 0.999
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.947
ADH60903.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: tpd:Teth39_1145 oxaloacetate decarboxylase.
  
 
 0.851
ADH61691.1
PFAM: sodium pump decarboxylase gamma subunit; KEGG: tpd:Teth39_0306 hypothetical protein.
     
 0.785
ADH60258.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate protein domain protein TPP-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; Pyruvate/ketoisovalerate oxidoreductase; KEGG: tpd:Teth39_1842 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
  
 0.582
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 0.557
fhs
KEGG: tpd:Teth39_0303 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.556
ADH61442.1
PFAM: AMP-dependent synthetase and ligase; KEGG: tpd:Teth39_0579 AMP-dependent synthetase and ligase.
 
 
 0.555
ADH61045.1
KEGG: tex:Teth514_1724 malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 
  
 0.513
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
  
 0.506
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (16%) [HD]