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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH61699.1SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: tex:Teth514_0790 phosphoprotein phosphatase; PFAM: Stage II sporulation E family protein. (783 aa)    
Predicted Functional Partners:
ADH61177.1
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.950
ADH61798.1
KEGG: tex:Teth514_0606 hypothetical protein; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.895
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.850
ADH59982.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: tex:Teth514_0108 regulatory protein, DeoR.
  
   
 0.844
ADH60871.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.837
ADH60850.1
KEGG: tex:Teth514_1525 AAA ATPase; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
   
 0.828
ADH61175.1
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.820
ADH60663.1
KEGG: tpd:Teth39_1401 stage II sporulation P family protein; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein.
  
   
 0.809
ADH60883.1
KEGG: tpd:Teth39_1120 anti-sigma-factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
  
  
 0.806
ADH60856.1
TIGRFAM: stage III sporulation protein AG; KEGG: tpd:Teth39_1094 hypothetical protein.
  
   
 0.799
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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