Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADH61699.1SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: tex:Teth514_0790 phosphoprotein phosphatase; PFAM: Stage II sporulation E family protein. (783 aa)    
Predicted Functional Partners:
ADH61177.1
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.945
ADH61798.1
KEGG: tex:Teth514_0606 hypothetical protein; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.857
ADH59982.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: tex:Teth514_0108 regulatory protein, DeoR.
  
   
 0.834
ADH60850.1
KEGG: tex:Teth514_1525 AAA ATPase; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
   
 0.823
ADH61156.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.801
ADH61175.1
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.801
ADH61809.1
KEGG: tpd:Teth39_0171 AbrB family transcriptional regulator; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein.
 
   
 0.800
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.797
ADH60856.1
TIGRFAM: stage III sporulation protein AG; KEGG: tpd:Teth39_1094 hypothetical protein.
  
   
 0.795
ADH60663.1
KEGG: tpd:Teth39_1401 stage II sporulation P family protein; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein.
  
   
 0.794
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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