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ADH61781.1methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (155 aa)    
Predicted Functional Partners:
ADH61279.1
PFAM: domain of unknown function DUF1730; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tpd:Teth39_0723 hypothetical protein.
     0.851
ADH59924.1
KEGG: tpd:Teth39_2153 DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase.
    
 0.697
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.652
ADH61782.1
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: tex:Teth514_0627 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.638
ADH61290.1
AAA ATPase central domain protein; KEGG: tpd:Teth39_0710 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
 
     0.630
ADH60258.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate protein domain protein TPP-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; Pyruvate/ketoisovalerate oxidoreductase; KEGG: tpd:Teth39_1842 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
     
 0.600
ADH60369.1
KEGG: tpd:Teth39_1728 8-oxoguanine DNA glycosylase domain-containing protein; PFAM: 8-oxoguanine DNA glycosylase domain protein; HhH-GPD family protein; SMART: HhH-GPD family protein; Helix-hairpin-helix DNA-binding class 1.
  
  
 0.502
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
   
 0.481
ADH61780.1
KEGG: tpd:Teth39_0209 transcriptional regulator, TrmB; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.
       0.476
ADH61771.1
PHP domain protein; KEGG: tex:Teth514_0650 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1.
     
 0.437
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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