Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61892.1KEGG: tpd:Teth39_0099 DNA replication protein DnaC; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase. (327 aa)    
Predicted Functional Partners:
ADH61891.1
KEGG: tpd:Teth39_0100 primosome, DnaD subunit; TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region.
 
 
 0.962
ADH61922.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 0.938
ADH60530.1
Manually curated; KEGG: tpd:Teth39_1525 hypothetical protein.
  
     0.700
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
     
 0.687
ADH61733.1
Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
     
  0.672
ADH61890.1
Peptidase M23; KEGG: tpd:Teth39_0101 peptidase M23B; PFAM: Peptidase M23; G5 domain protein; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
       0.619
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.613
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 
 0.569
ADH61570.1
PFAM: YbbR family protein; KEGG: tpd:Teth39_0458 YbbR family protein.
 
     0.516
ADH61214.1
Regulatory protein DeoR; KEGG: chy:CHY_0837 DNA repair protein RadA; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR.
  
 
 0.511
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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