Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH61935.1KEGG: tex:Teth514_2401 hypothetical protein. (167 aa)    
Predicted Functional Partners:
ADH61936.1
KEGG: tpd:Teth39_2283 cysteine desulfurase family protein; TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V.
       0.745
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.694
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.647
ADH61937.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: tpd:Teth39_2284 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
 
 0.597
ADH61938.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: tex:Teth514_2404 cobyrinic acid a,c-diamide synthase.
  
  
 0.577
ADH61939.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: tpd:Teth39_2286 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
 
 0.524
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.486
ADH60482.1
PFAM: conserved hypothetical protein; KEGG: tpd:Teth39_1609 hypothetical protein.
  
 
 0.430
cinA
Competence/damage-inducible protein CinA; KEGG: tpd:Teth39_1192 competence damage-inducible protein A; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family.
       0.413
ADH60661.1
PFAM: membrane protein of unknown function; KEGG: tpd:Teth39_1403 hypothetical protein.
  
     0.412
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.