STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN70317.1Oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
    
 0.898
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  
  
 
0.897
pdxT
Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.896
KUN70316.1
Pyridoxamine 5'-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.872
KUN64627.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.837
KUN57892.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.728
nnrD
Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...]
    
 0.613
KUN70315.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.596
KUN70312.1
Deazaflavin-dependent nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.546
KUN70314.1
acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.543
Your Current Organism:
Streptomyces canus
NCBI taxonomy Id: 58343
Other names: ATCC 12237, ATCC 19737, ATCC 23626 [[Streptomyces ciscaucasicus]], ATCC 23918 [[Streptomyces ciscaucasicus]], BCRC 13652, CBS 475.68, CBS 839.68 [[Streptomyces ciscaucasicus]], CCRC 13652, CCRC:13652, DSM 40017, DSM 40275 [[Streptomyces ciscaucasicus]], IFO 12752, IFO 12872 [[Streptomyces ciscaucasicus]], IMET 42945 [[Streptomyces ciscaucasicus]], INA 2022/55 [[Streptomyces ciscaucasicus]], ISP 5017, ISP 5275 [[Streptomyces ciscaucasicus]], JCM 4212, JCM 4384 [[Streptomyces ciscaucasicus]], JCM 4569, LMG 19329, LMG:19329, NBRC 12752, NBRC 12872 [[Streptomyces ciscaucasicus]], NCIMB 9627, NRRL B-16362 [[Streptomyces ciscaucasicus]], NRRL B-3980, NRRL-ISP 5017, NRRL-ISP 5275 [[Streptomyces ciscaucasicus]], S. canus, Streptomyces ciscaucasicus, Streptomyces ciscaucasius, UNIQEM 125, VKM Ac-998 [[Streptomyces ciscaucasicus]], actinobacterium Act5(2011)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.