STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN62096.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 0.915
KUN57704.1
Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.907
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.844
KUN68868.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.774
grpE-2
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
       0.770
KUN62095.1
Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.756
KUN73119.1
UDP-N-acetyl-D-glucosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.747
KUN62243.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.738
KUN61647.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.738
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 
 0.736
Your Current Organism:
Streptomyces canus
NCBI taxonomy Id: 58343
Other names: ATCC 12237, ATCC 19737, ATCC 23626 [[Streptomyces ciscaucasicus]], ATCC 23918 [[Streptomyces ciscaucasicus]], BCRC 13652, CBS 475.68, CBS 839.68 [[Streptomyces ciscaucasicus]], CCRC 13652, CCRC:13652, DSM 40017, DSM 40275 [[Streptomyces ciscaucasicus]], IFO 12752, IFO 12872 [[Streptomyces ciscaucasicus]], IMET 42945 [[Streptomyces ciscaucasicus]], INA 2022/55 [[Streptomyces ciscaucasicus]], ISP 5017, ISP 5275 [[Streptomyces ciscaucasicus]], JCM 4212, JCM 4384 [[Streptomyces ciscaucasicus]], JCM 4569, LMG 19329, LMG:19329, NBRC 12752, NBRC 12872 [[Streptomyces ciscaucasicus]], NCIMB 9627, NRRL B-16362 [[Streptomyces ciscaucasicus]], NRRL B-3980, NRRL-ISP 5017, NRRL-ISP 5275 [[Streptomyces ciscaucasicus]], S. canus, Streptomyces ciscaucasicus, Streptomyces ciscaucasius, UNIQEM 125, VKM Ac-998 [[Streptomyces ciscaucasicus]], actinobacterium Act5(2011)
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