STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN60403.1Carnitine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family. (411 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  0.767
sucC-2
Succinate--CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  0.767
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.708
sucD-2
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.708
KUN60404.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.675
KUN60402.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.643
KUN73255.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.602
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.601
KUN61292.1
Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.587
KUN72281.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.578
Your Current Organism:
Streptomyces canus
NCBI taxonomy Id: 58343
Other names: ATCC 12237, ATCC 19737, ATCC 23626 [[Streptomyces ciscaucasicus]], ATCC 23918 [[Streptomyces ciscaucasicus]], BCRC 13652, CBS 475.68, CBS 839.68 [[Streptomyces ciscaucasicus]], CCRC 13652, CCRC:13652, DSM 40017, DSM 40275 [[Streptomyces ciscaucasicus]], IFO 12752, IFO 12872 [[Streptomyces ciscaucasicus]], IMET 42945 [[Streptomyces ciscaucasicus]], INA 2022/55 [[Streptomyces ciscaucasicus]], ISP 5017, ISP 5275 [[Streptomyces ciscaucasicus]], JCM 4212, JCM 4384 [[Streptomyces ciscaucasicus]], JCM 4569, LMG 19329, LMG:19329, NBRC 12752, NBRC 12872 [[Streptomyces ciscaucasicus]], NCIMB 9627, NRRL B-16362 [[Streptomyces ciscaucasicus]], NRRL B-3980, NRRL-ISP 5017, NRRL-ISP 5275 [[Streptomyces ciscaucasicus]], S. canus, Streptomyces ciscaucasicus, Streptomyces ciscaucasius, UNIQEM 125, VKM Ac-998 [[Streptomyces ciscaucasicus]], actinobacterium Act5(2011)
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