STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSY45829.1MerR family regulatory protein. (112 aa)    
Predicted Functional Partners:
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha.
   
  0.744
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.627
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.584
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.584
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.584
OSY46970.1
Hypothetical protein.
  
     0.516
rcsC
Sensor histidine kinase RcsC.
   
 
 0.486
cph2_2
Phytochrome-like protein cph2.
    
 0.471
gmr
Cyclic di-GMP phosphodiesterase Gmr.
   
 0.470
dnaJ_1
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
   0.464
Your Current Organism:
Streptomyces platensis
NCBI taxonomy Id: 58346
Other names: ATCC 13865, ATCC 23948, BCRC 11898, CBS 310.56, CBS 932.68, CCRC 11898, CCRC:11898, CCUG 11118, DSM 40041, IFO 12901, ISP 5041, JCM 4189, JCM 4662, NBRC 12901, NCAIM B.01481, NCIMB 9607, NRRL 2364, NRRL B-5486, NRRL-ISP 5041, S. platensis, Streptomyces sp. CB00739
Server load: low (18%) [HD]