STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsH_2ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. (429 aa)    
Predicted Functional Partners:
ybiA
Swarming motility protein YbiA.
   
 
 0.906
acuC
Acetoin utilization protein AcuC.
   
 0.869
OSY47529.1
Sel1 repeat protein.
 
 
 0.860
htpG
Chaperone protein HtpG.
   
 0.842
OSY48419.1
Hypothetical protein.
   
 0.841
prcB
Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.836
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
   
 0.836
mpa
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
0.784
glpK_1
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
  0.775
glpK_2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
  0.775
Your Current Organism:
Streptomyces platensis
NCBI taxonomy Id: 58346
Other names: ATCC 13865, ATCC 23948, BCRC 11898, CBS 310.56, CBS 932.68, CCRC 11898, CCRC:11898, CCUG 11118, DSM 40041, IFO 12901, ISP 5041, JCM 4189, JCM 4662, NBRC 12901, NCAIM B.01481, NCIMB 9607, NRRL 2364, NRRL B-5486, NRRL-ISP 5041, S. platensis, Streptomyces sp. CB00739
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