node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AND11838.1 | AND14021.1 | AOUC001_02725 | AOUC001_14475 | Dihydroxyacetone kinase subunit DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
AND11838.1 | purR | AOUC001_02725 | AOUC001_08595 | Dihydroxyacetone kinase subunit DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.717 |
AND14021.1 | AND11838.1 | AOUC001_14475 | AOUC001_02725 | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxyacetone kinase subunit DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.523 |
AND14021.1 | gltB | AOUC001_14475 | AOUC001_16310 | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
AND14021.1 | guaA | AOUC001_14475 | AOUC001_07845 | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.602 |
AND14021.1 | purR | AOUC001_14475 | AOUC001_08595 | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.706 |
AND14021.1 | sodB | AOUC001_14475 | AOUC001_08600 | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.609 |
dusA | guaA | AOUC001_01795 | AOUC001_07845 | tRNA dihydrouridine synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.429 |
dusA | purR | AOUC001_01795 | AOUC001_08595 | tRNA dihydrouridine synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.472 |
gltB | AND14021.1 | AOUC001_16310 | AOUC001_14475 | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
gltB | guaA | AOUC001_16310 | AOUC001_07845 | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.583 |
gltB | purR | AOUC001_16310 | AOUC001_08595 | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.703 |
guaA | AND14021.1 | AOUC001_07845 | AOUC001_14475 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.602 |
guaA | dusA | AOUC001_07845 | AOUC001_01795 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA dihydrouridine synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.429 |
guaA | gltB | AOUC001_07845 | AOUC001_16310 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.583 |
guaA | purR | AOUC001_07845 | AOUC001_08595 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.422 |
pntB | purR | AOUC001_09660 | AOUC001_08595 | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.434 |
purR | AND11838.1 | AOUC001_08595 | AOUC001_02725 | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Dihydroxyacetone kinase subunit DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.717 |
purR | AND14021.1 | AOUC001_08595 | AOUC001_14475 | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.706 |
purR | dusA | AOUC001_08595 | AOUC001_01795 | Transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | tRNA dihydrouridine synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.472 |