node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aadA1 | sugE | AOUC001_19315 | AOUC001_16790 | ANT(3'') family aminoglycoside nucleotidyltransferase; Mediates bacterial resistance to the antibiotics streptomycin and spectomycin. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.416 |
aadA1 | sul1 | AOUC001_19315 | AOUC001_19860 | ANT(3'') family aminoglycoside nucleotidyltransferase; Mediates bacterial resistance to the antibiotics streptomycin and spectomycin. | Sulfonamide-resistant dihydropteroate synthase Sul1; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.930 |
frdB | frdC | AOUC001_16775 | AOUC001_16780 | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.999 |
frdB | frdD | AOUC001_16775 | AOUC001_16785 | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.999 |
frdB | sugE | AOUC001_16775 | AOUC001_16790 | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.574 |
frdC | frdB | AOUC001_16780 | AOUC001_16775 | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
frdC | frdD | AOUC001_16780 | AOUC001_16785 | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.999 |
frdC | sugE | AOUC001_16780 | AOUC001_16790 | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |
frdD | frdB | AOUC001_16785 | AOUC001_16775 | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
frdD | frdC | AOUC001_16785 | AOUC001_16780 | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.999 |
frdD | sugE | AOUC001_16785 | AOUC001_16790 | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.446 |
hybG-2 | hypA | AOUC001_16795 | AOUC001_16800 | Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.955 |
hybG-2 | sugE | AOUC001_16795 | AOUC001_16790 | Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.492 |
hypA | hybG-2 | AOUC001_16800 | AOUC001_16795 | Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.955 |
hypA | sugE | AOUC001_16800 | AOUC001_16790 | Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.492 |
mdtK | sugE | AOUC001_08570 | AOUC001_16790 | MATE family efflux transporter; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.481 |
sugE | aadA1 | AOUC001_16790 | AOUC001_19315 | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | ANT(3'') family aminoglycoside nucleotidyltransferase; Mediates bacterial resistance to the antibiotics streptomycin and spectomycin. | 0.416 |
sugE | frdB | AOUC001_16790 | AOUC001_16775 | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.574 |
sugE | frdC | AOUC001_16790 | AOUC001_16780 | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.447 |
sugE | frdD | AOUC001_16790 | AOUC001_16785 | Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.446 |