STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Apau_0044NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155:IPR013785; KEGG: cdl:CDR20291_2962 predicted enoate reductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: C6PZ44 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase / NADH oxidase family. (452 aa)    
Predicted Functional Partners:
Apau_0101
Redox-active disulfide protein 2; InterPro IPR005243:IPR012336:IPR012335; KEGG: mma:MM_0737 hypothetical protein; SPTR: Q8PYW2 Conserved protein; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2.
  
 0.995
Apau_0181
Hypothetical protein; InterPro IPR012336; KEGG: rpr:RP397 thiol:disulfide interchange protein TlpA (TlpA); SPTR: D1C832 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen.
  
 0.995
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.979
Apau_0757
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR002869:IPR009014:IPR 002880:IPR019752:IPR019456:IPR001450:IPR011766:IPR017900:I PR015941; KEGG: tai:Taci_1436 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D1B6M5 Pyruvate [...]
    
 0.972
Apau_0178
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR016156:IPR001763; KEGG: tai:Taci_0103 pyridine nucleotide-disulphide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: D1B7U0 Pyridine nucleotide-disulphide oxidoreductase dimerization region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disu [...]
  
 0.945
Apau_1952
FAD dependent oxidoreductase; COGs: COG0579 dehydrogenase; InterPro IPR006076:IPR007419; KEGG: tai:Taci_1552 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: D1B6Y2 FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase.
  
 
 0.942
Apau_2005
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR012255:IPR014729:IPR014730; KEGG: kol:Kole_1998 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: C5CH75 Electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein domain.
  
 
 0.940
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.933
Apau_1260
COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR013027:IPR005982:IPR000103; KEGG: tai:Taci_0823 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D1B9V3 Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 0.901
Apau_0756
FAD dependent oxidoreductase; InterPro IPR013027:IPR006076; KEGG: bth:BT_0434 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: C1TQF5 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: FAD dependent oxidoreductase.
  
 0.889
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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