STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Apau_0157Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR000878:IPR013216:IPR014777; KEGG: tai:Taci_0051 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase type 11; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: D1B7N8 Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Tetrapy [...] (429 aa)    
Predicted Functional Partners:
Apau_0155
Cobalamin (vitamin B12) biosynthesis CbiG protein; COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR003723:IPR014777; KEGG: tai:Taci_0049 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-6x reductase CbiJ/CobK; SPTR: D1B7N6 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PFAM: Precorrin-6x reductase CbiJ/CobK; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; C [...]
 
 0.999
Apau_0156
COGs: COG2875 Precorrin-4 methylase; InterProIPR006362:IPR000878:IPR003043:IPR014777:IPR 014776; KEGG: tai:Taci_0050 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: D1B7N7 Precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.999
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 0.999
Apau_0161
Precorrin-8X methylmutase CbiC/CobH; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tai:Taci_0055 precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: D1B7P2 Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase.
 
 
 0.999
Apau_0153
COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR012382:IPR014777; KEGG: tai:Taci_0048 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: C1TM51 Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.996
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.993
Apau_0160
Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388:IPR019758; KEGG: tai:Taci_0054 sirohydrochlorin cobaltochelatase; PFAM: anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: D1B7P1 Sirohydrochlorin cobaltochelatase; PFAM: Cobalt chelatase (CbiK).
 
  
 0.969
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.955
Apau_0150
COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain.
 
  
 0.952
Apau_0148
COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
 
  
 0.921
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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