node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apau_0148 | Apau_0150 | Apau_0148 | Apau_0150 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | 0.998 |
Apau_0148 | Apau_0153 | Apau_0148 | Apau_0153 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR012382:IPR014777; KEGG: tai:Taci_0048 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: C1TM51 Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.992 |
Apau_0148 | Apau_0155 | Apau_0148 | Apau_0155 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin (vitamin B12) biosynthesis CbiG protein; COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR003723:IPR014777; KEGG: tai:Taci_0049 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-6x reductase CbiJ/CobK; SPTR: D1B7N6 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PFAM: Precorrin-6x reductase CbiJ/CobK; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; C [...] | 0.994 |
Apau_0148 | Apau_0156 | Apau_0148 | Apau_0156 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG2875 Precorrin-4 methylase; InterProIPR006362:IPR000878:IPR003043:IPR014777:IPR 014776; KEGG: tai:Taci_0050 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: D1B7N7 Precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.915 |
Apau_0148 | Apau_0157 | Apau_0148 | Apau_0157 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR000878:IPR013216:IPR014777; KEGG: tai:Taci_0051 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase type 11; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: D1B7N8 Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Tetrapy [...] | 0.921 |
Apau_0148 | Apau_0160 | Apau_0148 | Apau_0160 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388:IPR019758; KEGG: tai:Taci_0054 sirohydrochlorin cobaltochelatase; PFAM: anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: D1B7P1 Sirohydrochlorin cobaltochelatase; PFAM: Cobalt chelatase (CbiK). | 0.936 |
Apau_0148 | Apau_0161 | Apau_0148 | Apau_0161 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Precorrin-8X methylmutase CbiC/CobH; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tai:Taci_0055 precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: D1B7P2 Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | 0.827 |
Apau_0148 | cbiD | Apau_0148 | Apau_0158 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.868 |
Apau_0148 | cobD | Apau_0148 | Apau_1772 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.695 |
Apau_0148 | cobQ | Apau_0148 | Apau_0186 | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.874 |
Apau_0150 | Apau_0148 | Apau_0150 | Apau_0148 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.998 |
Apau_0150 | Apau_0153 | Apau_0150 | Apau_0153 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR012382:IPR014777; KEGG: tai:Taci_0048 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: C1TM51 Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.955 |
Apau_0150 | Apau_0155 | Apau_0150 | Apau_0155 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | Cobalamin (vitamin B12) biosynthesis CbiG protein; COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR003723:IPR014777; KEGG: tai:Taci_0049 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-6x reductase CbiJ/CobK; SPTR: D1B7N6 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PFAM: Precorrin-6x reductase CbiJ/CobK; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; C [...] | 0.980 |
Apau_0150 | Apau_0156 | Apau_0150 | Apau_0156 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | COGs: COG2875 Precorrin-4 methylase; InterProIPR006362:IPR000878:IPR003043:IPR014777:IPR 014776; KEGG: tai:Taci_0050 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: D1B7N7 Precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.694 |
Apau_0150 | Apau_0157 | Apau_0150 | Apau_0157 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR000878:IPR013216:IPR014777; KEGG: tai:Taci_0051 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase type 11; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: D1B7N8 Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Tetrapy [...] | 0.952 |
Apau_0150 | Apau_0160 | Apau_0150 | Apau_0160 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388:IPR019758; KEGG: tai:Taci_0054 sirohydrochlorin cobaltochelatase; PFAM: anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: D1B7P1 Sirohydrochlorin cobaltochelatase; PFAM: Cobalt chelatase (CbiK). | 0.759 |
Apau_0150 | cbiD | Apau_0150 | Apau_0158 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.602 |
Apau_0150 | cobQ | Apau_0150 | Apau_0186 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.566 |
Apau_0153 | Apau_0148 | Apau_0153 | Apau_0148 | COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR012382:IPR014777; KEGG: tai:Taci_0048 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: C1TM51 Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR000878:IPR003754:IPR014777:IPR 014776; KEGG: tai:Taci_0043 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: D1B7N0 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.992 |
Apau_0153 | Apau_0150 | Apau_0153 | Apau_0150 | COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR012382:IPR014777; KEGG: tai:Taci_0048 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: C1TM51 Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040; KEGG: tai:Taci_0045 siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein; SPTR: D1B7N2 Siroheme synthase (Precorrin-2 oxidase/ferrochelatase domain)-like protein; TIGRFAM: siroheme synthase, N-terminal domain. | 0.955 |