STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_0276CRISPR-associated protein Cas5, Hmari subtype; InterPro IPR013421:IPR013422:IPR007552; KEGG: pmo:Pmob_1880 CRISPR-associated Cas5 family Hmari subtype protein; PFAM: protein of unknown function DUF522; SPTR: C1TQC8 CRISPR-associated protein Cas5, Hmari subtype; TIGRFAM: CRISPR-associated protein Cas5, Hmari subtype; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Hmari subtype; CRISPR-associated protein Cas5, N-terminal domain. (236 aa)    
Predicted Functional Partners:
Apau_0275
Metal dependent phosphohydrolase; COGs: COG1203 helicase; InterPro IPR006474:IPR006674:IPR003607; KEGG: pmo:Pmob_1879 CRISPR-associated helicase Cas3; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1TQC9 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: HD domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD.
 
 
 0.982
Apau_0277
CRISPR-associated protein, Csh2 family; COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482:IPR013419; KEGG: swo:Swol_2520 hypothetical protein; PFAM: CRISPR-associated protein TM1801; SPTR: C1TQC7 CRISPR-associated protein, Csh2 family; TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csh2 family.
 
  
 0.961
Apau_0274
CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.954
cas1-2
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.912
Apau_0272
CRISPR-associated protein, Cas2 family; COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR003799; KEGG: gwc:GWCH70_0311 CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; SPTR: C1TQD2 CRISPR-associated protein, Cas2 family; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2.
 
   
 0.910
Apau_0279
CRISPR-associated protein Cas6; COGs: COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR010156:IPR002743; KEGG: dhd:Dhaf_3942 CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; SPTR: C1TQC4 CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein Cas6; PFAM: CRISPR associated protein Cas6; TIGRFAM: CRISPR-associated endoribonuclease Cas6.
 
   
 0.887
Apau_0538
CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterPro IPR014021:IPR001650:IPR006474; KEGG: sth:STH664 putative helicase; PFAM: helicase domain protein; SMART: helicase domain protein; SPTR: C1XFZ7 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD.
  
 
 0.694
Apau_0278
KEGG: swo:Swol_2522 hypothetical protein; SPTR: C1TQC5 CRISPR-associated protein TM1802 (Cas_TM1802); PFAM: CRISPR-associated protein TM1802 (cas_TM1802).
  
    0.621
Apau_0024
KEGG: cbt:CLH_1382 microcompartments protein; SPTR: B2UZN0 Microcompartments protein.
  
     0.455
Apau_1886
Metal dependent phosphohydrolase; InterPro IPR006675:IPR006674; KEGG: tai:Taci_1363 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: D1B6F3 Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
  
     0.408
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.