STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_0351COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011761:IPR005483:IPR013817:IPR013816:IPR 005479:IPR016185:IPR005480:IPR006275:IPR005481; KEGG: sti:Sthe_0936 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; SPTR: C1TLQ6 Carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; [...] (1044 aa)    
Predicted Functional Partners:
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR017926:IPR001317:IPR011702:IPR006220:IPR 002474:IPR006274:IPR000991; KEGG: adg:Adeg_0372 carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; SPTR: C9RB99 Carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 0.999
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR006132:IPR006131:IPR002082; KEGG: tai:Taci_1092 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: D1B5N3 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to the aspa [...]
 
 0.999
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR014729:IPR018223; KEGG: tai:Taci_0753 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: D1B9N3 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.995
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.993
Apau_1995
Dihydropyrimidinase; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR011059:IPR011778:IPR006680; KEGG: tai:Taci_0430 dihydropyrimidinase; PFAM: amidohydrolase; SPTR: D1B8R4 Dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase; dihydroorotase, multifunctional complex type.
 
 0.990
Apau_2001
Selenate reductase YgfK; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR009051:IPR000759:IPR012285:IPR017701:IPR 002937; KEGG: tai:Taci_0423 selenate reductase YgfK; PFAM: amine oxidase; SPTR: D1B8Q7 Selenate reductase YgfK; TIGRFAM: selenate reductase YgfK; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: putative selenate reductase, YgfK subunit.
  
 0.985
Apau_1423
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
 
 0.976
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 
 0.974
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.948
dapF-2
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
   
 0.942
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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