STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_0499Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (243 aa)    
Predicted Functional Partners:
Apau_2245
Phosphate ABC transporter membrane protein 2, PhoT family; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: tai:Taci_0093 phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C1TMW7 Phosphate ABC transporter membrane protein 2, PhoT family; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.
  
 0.974
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
 0.972
Apau_2243
Phosphate ABC transporter substrate-binding protein, PhoT family; COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862:IPR006059; KEGG: tai:Taci_0095 phosphate binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: D1B7T2 Phosphate binding protein; TIGRFAM: phosphate binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate binding protein.
 
  
 0.874
Apau_2244
Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.823
buk-2
COGs: COG3426 Butyrate kinase; InterPro IPR000890:IPR011245; KEGG: gyc:GYMC61_0263 butyrate kinase; PFAM: acetate and butyrate kinase; SPTR: C1TPD2 Butyrate kinase; TIGRFAM: butyrate kinase; PFAM: Acetokinase family; TIGRFAM: butyrate kinase; Belongs to the acetokinase family.
       0.762
Apau_0497
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR016040:IPR006140:IPR006139; KEGG: cno:NT01CX_0601 D-isomer specific 2-hydroxyacid dehydrogenases; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: C0CTY9 Putative uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
       0.762
Apau_0498
KEGG: tai:Taci_0455 hypothetical protein; SPTR: D1B8T8 Putative uncharacterized protein.
       0.762
Apau_0495
Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR012147:IPR014079:IPR002505; KEGG: tai:Taci_0453 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: D1B8T6 Phosphate butyryltransferase; TIGRFAM: phosphate butyryltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase.
       0.545
Apau_0379
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR004358:IPR003018:IPR000014:IPR 003661:IPR003594:IPR009082:IPR011006:IPR013656; KEGG: chl:Chy400_0428 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: B9LID2 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kina [...]
  
  
 0.498
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.471
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.