STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_0873CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467:IPR002545:IPR008207:IPR004358:IPR 003594:IPR009082:IPR010808:IPR004105; KEGG: tai:Taci_1310 CheA signal transduction histidine kinase; PFAM: Signal transducing histidine kinase homodimeric; P2 response regulator binding domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: D1B6A0 CheA signal transduction histidine kina [...] (690 aa)    
Predicted Functional Partners:
Apau_0552
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545:IPR011006; KEGG: tai:Taci_1572 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; SPTR: D1B702 Response regulator receiver modulated CheW protein; PFAM: CheW-like domain; Response regulator receiver domain.
 0.999
Apau_0861
COGs: COG1886 Flagellar motor switch/type III secretory pathway protein; InterPro IPR012826:IPR001172:IPR001543; KEGG: tai:Taci_1322 flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; SPTR: D1B6B2 Flagellar motor switch protein FliN; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: type III secretion system apparatus protein YscQ/HrcQ; flagellar motor switch protein FliN.
 
 0.999
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.999
Apau_0379
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR004358:IPR003018:IPR000014:IPR 003661:IPR003594:IPR009082:IPR011006:IPR013656; KEGG: chl:Chy400_0428 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: B9LID2 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kina [...]
  
 0.997
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.997
Apau_0721
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: rce:RC1_0343 chemotaxis signal transduction protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: C1TRZ9 Chemotaxis signal transduction protein; PFAM: CheW-like domain.
 
 0.995
Apau_1945
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tai:Taci_1537 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: D1B6W7 CheW protein; PFAM: CheW-like domain.
 
 0.995
Apau_0386
Methyl-accepting chemotaxis sensory transducer with Cache sensor; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660:IPR004010; KEGG: tai:Taci_0556 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: D1B939 Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signalin [...]
 
 0.988
cheD
CheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 
 0.988
Apau_2164
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR008207:IPR 005467:IPR001789:IPR000014:IPR004358:IPR003661:IPR013656; KEGG: dma:DMR_28640 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C4XHI1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: [...]
  
 0.988
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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