STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (762 aa)    
Predicted Functional Partners:
Apau_0903
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 0.999
Apau_0897
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 0.996
kdsB
3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.986
Apau_0902
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644:IPR004800:IPR001347; KEGG: tai:Taci_1281 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SMART: CBS domain containing protein; SPTR: D1B671 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.984
Apau_0896
Protein of unknown function DUF1009; COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: tai:Taci_1287 protein of unknown function DUF1009; PFAM: protein of unknown function DUF1009; SPTR: D1B677 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1009).
 
   
 0.971
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006269:IPR006218:IPR013785; KEGG: tai:Taci_1282 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; SPTR: D1B672 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase.
 
   
 0.969
Apau_0199
Conserved hypothetical protein; COGs: COG0763 Lipid A disaccharide synthetase; KEGG: tai:Taci_0132 hypothetical protein; SPTR: D1B7W9 Putative uncharacterized protein; PFAM: Lipid-A-disaccharide synthetase; Belongs to the LpxB family.
 
  
 0.958
Apau_0893
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.950
lpxC
UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.947
Apau_0895
Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: tai:Taci_1288 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: D1B678 Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family.
 
     0.946
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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