STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1057InterPro IPR002145; KEGG: dma:DMR_42740 hypothetical protein; PFAM: CopG domain protein DNA-binding domain protein; SPTR: C4XQN1 Putative uncharacterized protein; PFAM: Ribbon-helix-helix protein, copG family. (77 aa)    
Predicted Functional Partners:
Apau_1058
Plasmid stabilization system; COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR007712; KEGG: kse:Ksed_24250 addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; SPTR: A7BAH6 Putative uncharacterized protein; PFAM: Plasmid stabilisation system protein.
     
 0.806
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
    
   0.518
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.518
Apau_1061
Plasmid stabilization system; InterPro IPR007712; KEGG: geo:Geob_0186 plasmid stabilization system; PFAM: plasmid stabilization system; SPTR: C0XQS2 Plasmid stabilization system protein; manually curated; PFAM: Plasmid stabilisation system protein.
     
 0.515
Apau_1605
COGs: COG4786 Flagellar basal body rod protein; InterProIPR001444:IPR010930:IPR020013:IPR012834:IPR 019776; KEGG: tai:Taci_1147 flagellar basal-body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: D1B5T8 Flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria.
    
   0.511
Apau_1606
COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444:IPR010930:IPR020013:IPR019776; KEGG: tai:Taci_1148 protein of unknown function DUF1078 domain protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: D1B5T9 Putative uncharacterized protein; TIGRFAM: fagellar hook-basal body protein; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: fagellar hook-basal body proteins.
    
   0.511
Apau_1059
DNA polymerase beta domain protein region; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: lch:Lcho_0357 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: B1XWA5 DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain.
       0.482
Apau_1056
KEGG: aau:AAur_pTC20020 hypothetical protein; SPTR: C0BU89 Putative uncharacterized protein.
       0.454
Apau_1060
Hypothetical protein; KEGG: npu:Npun_R1756 prevent-host-death family protein; SPTR: Q2IUQ3 Aminotransferase.
       0.450
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.