STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1168Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR012202:IPR003495; KEGG: adg:Adeg_2010 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: C1TPS6 Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. (220 aa)    
Predicted Functional Partners:
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.996
Apau_0936
Hydrogenase formation HypD protein; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: glo:Glov_3063 hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; SPTR: C1TK22 Hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.961
Apau_2197
COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: tai:Taci_0213 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D1B849 Peptidylprolyl isomerase FKBP-type; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
    
 
 0.913
Apau_1533
COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001501:IPR001135:IPR018194; KEGG: mla:Mlab_0959 membrane bound hydrogenase subunit MbhL; PFAM: nickel-dependent hydrogenase large subunit; NADH-ubiquinone oxidoreductase chain 49kDa; SPTR: C1TPP0 Ni,Fe-hydrogenase III large subunit; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
   
 
 0.856
Apau_1171
CBS domain containing protein; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR000644:IPR002646:IPR013785; KEGG: tai:Taci_0750 CBS domain containing protein; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; Polynucleotide adenylyltransferase region; SMART: CBS domain containing protein; SPTR: D1B9N0 CBS domain containing protein; manually curated; PFAM: DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.851
Apau_0937
InterPro IPR001109; KEGG: pab:PAB7315 hydrogenase expression/formation protein; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); SPTR: C1TK21 Hydrogenase maturation factor; PFAM: HupF/HypC family.
  
  
 0.848
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.841
Apau_1534
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG3262 Ni Fe-hydrogenase III component G; InterPro IPR001268; KEGG: tsi:TSIB_1285 membrane-bound hydrogenase MBH 2, subunit Mbh2K (hydrogenase subunit); PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: C1TPN9 Ni,Fe-hydrogenase III component G; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
   
 
 0.839
Apau_1971
(NiFe) hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterProIPR017945:IPR001792:IPR004421:IPR017968:IPR 006070:IPR011125; KEGG: sat:SYN_00600 hydrogenase maturation protein; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; SPTR: C1TMC9 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
   
 0.836
Apau_0935
Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854:IPR000728:IPR010918:IPR016188; KEGG: wsu:WS0795 hydrogenase expression/formation protein; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; SPTR: C1TK23 Hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
  
 0.833
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.