STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1209Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR006675:IPR013976:IPR003607; KEGG: tai:Taci_0779 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: D1B9Q9 Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG. (296 aa)    
Predicted Functional Partners:
Apau_0456
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014:IPR000700:IPR000160:IPR013656; KEGG: tai:Taci_1587 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: D1B717 Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
  
  0.921
Apau_2153
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR011006:IPR005829:IPR001789:IPR000160; KEGG: gsu:GSU2313 response regulator; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Q74AN9 Response regulator; TIGRFAM: diguanylate cyclase; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
  0.863
Apau_1214
Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: tai:Taci_0784 protein of unknown function DUF370; PFAM: protein of unknown function DUF370; SPTR: D1B9R4 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family.
   
   0.817
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR000623:IPR011994; KEGG: tai:Taci_0780 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: D1B9R0 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; Shikimate kinase; TIGRFAM: cytidylate kinase.
       0.810
Apau_1211
COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tai:Taci_0781 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: D1B9R1 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
       0.810
hflX
GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.810
Apau_1213
Domain of unknown function DUF1732; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR005229:IPR013527:IPR013551; KEGG: tai:Taci_0783 domain of unknown function DUF1732; PFAM: domain of unknown function DUF1732; YicC domain protein; SPTR: D1B9R3 Putative uncharacterized protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255.
       0.808
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
       0.794
Apau_1217
Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.793
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.771
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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