STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1223InterPro IPR016196:IPR011701; KEGG: dae:Dtox_2819 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: C1TP49 Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily. (391 aa)    
Predicted Functional Partners:
Apau_0225
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase.
   
 
  0.596
Apau_1755
COGs: COG0077 Prephenate dehydratase; InterProIPR008242:IPR002701:IPR001086:IPR020822:IPR 002912; KEGG: tai:Taci_1644 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: C1TR93 Prephenate dehydratase; PFAM: Prephenate dehydratase; Chorismate mutase type II; ACT domain.
  
 
 0.594
Apau_1224
Protein of unknown function methylase putative; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR002052:IPR016065:IPR004398; KEGG: tai:Taci_1108 protein of unknown function methylase putative; PFAM: Protein of unknown function methylase putative; SPTR: D1B5P9 Putative uncharacterized protein; manually curated; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family.
       0.571
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.519
Apau_0379
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR004358:IPR003018:IPR000014:IPR 003661:IPR003594:IPR009082:IPR011006:IPR013656; KEGG: chl:Chy400_0428 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: B9LID2 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kina [...]
    
 0.509
Apau_2164
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR008207:IPR 005467:IPR001789:IPR000014:IPR004358:IPR003661:IPR013656; KEGG: dma:DMR_28640 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C4XHI1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: [...]
     
 0.502
Apau_0756
FAD dependent oxidoreductase; InterPro IPR013027:IPR006076; KEGG: bth:BT_0434 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: C1TQF5 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: FAD dependent oxidoreductase.
 
  
 0.487
Apau_1448
COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterProIPR016040:IPR006140:IPR006139:IPR002912:IPR 006236; KEGG: aae:aq_1905 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; SPTR: C1SGT4 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic do [...]
  
 
  0.470
Apau_0212
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR016040; KEGG: tpd:Teth39_1970 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: A5TSY9 Possible dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
  
 
  0.457
Apau_0733
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR004358:IPR001610:IPR003661:IPR003594:IPR011006:I PR009082:IPR013655:IPR013767:IPR013656; KEGG: tai:Taci_1451 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC rep [...]
     
 0.444
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.