STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Apau_12373-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)    
Predicted Functional Partners:
Apau_1234
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterProIPR016035:IPR016036:IPR001227:IPR014043:IPR 004410; KEGG: tai:Taci_1098 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: D1B5N9 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 0.999
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.998
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 0.993
fabZ
3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.987
Apau_1235
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 0.987
Apau_1233
Enoyl-(acyl-carrier-protein) reductase II; COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR013785:IPR004136:IPR017569; KEGG: tai:Taci_1099 enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase NPD; SPTR: D1B5P0 Enoyl-(Acyl-carrier-protein) reductase II; TIGRFAM: enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase; TIGRFAM: putative enoyl-(acyl-carrier-protein) reductase II.
 
 
 0.970
Apau_1592
Putative sigma E regulatory protein, MucB/RseB; InterPro IPR016039; KEGG: tai:Taci_1135 betaine reductase; SPTR: D1B5S6 Betaine reductase.
  
 
 0.900
Apau_2136
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
    
 0.894
Apau_0757
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR002869:IPR009014:IPR 002880:IPR019752:IPR019456:IPR001450:IPR011766:IPR017900:I PR015941; KEGG: tai:Taci_1436 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D1B6M5 Pyruvate [...]
  
 
 0.881
Apau_0408
Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089:IPR001882:IPR011053; KEGG: tai:Taci_0293 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: D1B8C7 Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme.
  
 
 0.846
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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