STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1663Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014021:IPR001650:IPR006935:IPR014001; KEGG: hoh:Hoch_0896 type III restriction protein res subunit; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: C1TKV6 DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. (463 aa)    
Predicted Functional Partners:
Apau_1528
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR002298:IPR020046:IPR020047:IPR001098:IPR 018320:IPR002421:IPR008918:IPR020045:IPR019760; KEGG: tai:Taci_1079 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; DNA-directed DNA polymerase; SPTR: D1B5M0 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonucleas [...]
  
 0.994
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.992
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.992
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.992
Apau_0067
SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR000330:IPR001650:IPR014001:IPR014021; KEGG: plt:Plut_0902 DEAD/DEAH box helicase-like; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q3B4G7 DEAD/DEAH box helicase-like; PFAM: SNF2 Helicase protein; Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
 
 
 0.963
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.938
Apau_0401
KEGG: tai:Taci_0287 hypothetical protein; SPTR: D1B8C1 Putative uncharacterized protein.
    
  0.933
Apau_1067
KEGG: tai:Taci_0662 hypothetical protein; SPTR: D1B9E5 Putative uncharacterized protein.
    
  0.933
Apau_1667
TOPRIM domain protein; COGs: COG4643 conserved hypothetical protein; InterPro IPR006171:IPR006154:IPR003593; KEGG: ddc:Dd586_3771 P4 alpha zinc-binding domain protein; PFAM: TOPRIM domain protein; SMART: Toprim sub domain protein; AAA ATPase; SPTR: C8QS02 P4 alpha zinc-binding domain protein; PFAM: Toprim domain.
     
 0.858
Apau_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
  0.843
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.