STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1755COGs: COG0077 Prephenate dehydratase; InterProIPR008242:IPR002701:IPR001086:IPR020822:IPR 002912; KEGG: tai:Taci_1644 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: C1TR93 Prephenate dehydratase; PFAM: Prephenate dehydratase; Chorismate mutase type II; ACT domain. (356 aa)    
Predicted Functional Partners:
Apau_1753
COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268:IPR013785; KEGG: tai:Taci_1639 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: C1TR75 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
 
 0.998
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.997
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.995
Apau_1752
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099:IPR016040; KEGG: tai:Taci_1638 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: C1TR74 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
 
 0.990
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.986
Apau_1756
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999:IPR015890:IPR005801; KEGG: acr:Acry_1234 anthranilate synthase component I; PFAM: Chorismate binding-like; PRIAM: Anthranilate synthase; SPTR: C1TRA8 Anthranilate/para-aminobenzoate synthase component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme.
 
 
 0.981
Apau_1757
COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006220:IPR011702:IPR001317:IPR017926:IPR 000991:IPR006221; KEGG: ppd:Ppro_1581 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: A1APC6 Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
 
 
 0.979
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.978
Apau_2287
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004838:IPR001176:IPR015421:IPR 004839; KEGG: tro:trd_1303 aspartate aminotransferase A; PFAM: aminotransferase class I and II; SPTR: C6PQ09 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
 
 
 0.968
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR000623:IPR011994; KEGG: tai:Taci_0780 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: D1B9R0 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; Shikimate kinase; TIGRFAM: cytidylate kinase.
 
 
 0.953
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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