STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_1944PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR016195:IPR003141:IPR004013; KEGG: tai:Taci_1536 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: D1B6W6 PHP domain protein; PFAM: PHP domain. (276 aa)    
Predicted Functional Partners:
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
    
 0.905
Apau_1941
COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: tai:Taci_1534 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; PRIAM: N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin; SPTR: D1B6W4 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase.
       0.766
Apau_1943
COGs: COG2008 Threonine aldolase; InterPro IPR015424:IPR015421:IPR015422:IPR001597; KEGG: tai:Taci_1535 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: C1TS32 Threonine aldolase; PFAM: Beta-eliminating lyase.
       0.766
Apau_1942
Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: chy:CHY_0656 putative PmbA protein; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: C1TS33 Predicted Zn-dependent protease-like protein; PFAM: Putative modulator of DNA gyrase.
       0.765
Apau_0757
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR002869:IPR009014:IPR 002880:IPR019752:IPR019456:IPR001450:IPR011766:IPR017900:I PR015941; KEGG: tai:Taci_1436 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D1B6M5 Pyruvate [...]
    
  0.761
Apau_1270
COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.715
Apau_1947
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: tai:Taci_1539 phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; SPTR: D1B6W9 Phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
  
    0.650
Apau_1940
KEGG: tai:Taci_1533 hypothetical protein; SPTR: D1B6W3 Putative uncharacterized protein.
       0.634
Apau_1945
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tai:Taci_1537 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: D1B6W7 CheW protein; PFAM: CheW-like domain.
       0.614
Apau_1938
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.612
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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