STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_2046COGs: COG0515 Serine/threonine protein kinase; InterProIPR011009:IPR017441:IPR011990:IPR020635:IPR 002290:IPR019734:IPR000719:IPR013026:IPR017442:IPR013105; KEGG: tai:Taci_1698 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; Tetratricopeptide TPR_2 repeat protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; Tetratricopeptide repeat; SPTR: D1B7C1 Serine/threonine protein kinase; PFAM: Protein kinase domain. (516 aa)    
Predicted Functional Partners:
Apau_2047
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932:IPR014045; KEGG: amu:Amuc_0616 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: B4D8F5 Protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E (SpoIIE).
 
 0.987
Apau_0379
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR004358:IPR003018:IPR000014:IPR 003661:IPR003594:IPR009082:IPR011006:IPR013656; KEGG: chl:Chy400_0428 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: B9LID2 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kina [...]
   
 0.914
Apau_2164
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR008207:IPR 005467:IPR001789:IPR000014:IPR004358:IPR003661:IPR013656; KEGG: dma:DMR_28640 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C4XHI1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: [...]
   
 0.914
Apau_0733
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR004358:IPR001610:IPR003661:IPR003594:IPR011006:I PR009082:IPR013655:IPR013767:IPR013656; KEGG: tai:Taci_1451 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC rep [...]
   
 0.896
Apau_2154
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR008207:IPR009082:IPR 006118:IPR005467:IPR001789:IPR000014:IPR000700:IPR006189:I PR004358:IPR001610:IPR003661:IPR013655; KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; CHASE domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; resp [...]
   
 0.884
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.785
Apau_0361
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 004358:IPR001610:IPR003661:IPR003594:IPR011006:IPR009082:I PR013656; KEGG: glo:Glov_3522 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: B [...]
    
 0.782
Apau_2048
KEGG: hypothetical protein; K08155 MFS transporter, DHA1 family, solute carrier family 18 (vesicular monoamine); SPTR: C3ZTN5 Putative uncharacterized protein.
       0.773
Apau_2190
Putative PAS/PAC sensor protein; InterPro IPR011006:IPR001789:IPR000014:IPR013656; KEGG: mem:Memar_1158 putative PAS/PAC sensor protein; PFAM: PAS fold-4 domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: C1TPJ4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box.
 
  
 0.751
Apau_0299
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterProIPR000014:IPR000160:IPR013655:IPR001610:IPR 000700; KEGG: met:M446_3902 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: B0UG16 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF [...]
    
 0.745
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.