STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_2154COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR008207:IPR009082:IPR 006118:IPR005467:IPR001789:IPR000014:IPR000700:IPR006189:I PR004358:IPR001610:IPR003661:IPR013655; KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; CHASE domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; resp [...] (1513 aa)    
Predicted Functional Partners:
Apau_0379
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR004358:IPR003018:IPR000014:IPR 003661:IPR003594:IPR009082:IPR011006:IPR013656; KEGG: chl:Chy400_0428 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: B9LID2 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kina [...]
 
0.999
Apau_0708
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 004358:IPR001610:IPR003661:IPR003594:IPR011006:IPR009082:I PR013656; KEGG: dol:Dole_3272 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing [...]
 
0.999
Apau_2164
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR008207:IPR 005467:IPR001789:IPR000014:IPR004358:IPR003661:IPR013656; KEGG: dma:DMR_28640 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C4XHI1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: [...]
 
0.999
Apau_0378
Multi-sensor signal transduction histidine kinase; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR005467:IPR001789:IPR003594:IPR011006:IPR 009082:IPR013767; KEGG: cag:Cagg_3134 multi-sensor signal transduction histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; SPTR: A7BZ48 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regu [...]
0.998
Apau_0451
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR001633:IPR000160:IPR013163:IPR 013767; KEGG: dar:Daro_1909 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; Cache type 2 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: Q47ES6 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: di [...]
 
 0.998
Apau_0733
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR004358:IPR001610:IPR003661:IPR003594:IPR011006:I PR009082:IPR013655:IPR013767:IPR013656; KEGG: tai:Taci_1451 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC rep [...]
 
0.998
Apau_1725
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR005467:IPR001789:IPR000014:IPR 000700:IPR013767:IPR003661:IPR003594:IPR001610:IPR011006:I PR009082; KEGG: dol:Dole_3272 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator receiver; SP [...]
 
0.998
Apau_2040
Diguanylate cyclase and metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR000014:IPR000160:IPR000700:IPR013656:IPR 006674; KEGG: tai:Taci_1694 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: D1B7B7 Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: HD domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain [...]
 
 0.998
Apau_2153
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR011006:IPR005829:IPR001789:IPR000160; KEGG: gsu:GSU2313 response regulator; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Q74AN9 Response regulator; TIGRFAM: diguanylate cyclase; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
0.998
Apau_2190
Putative PAS/PAC sensor protein; InterPro IPR011006:IPR001789:IPR000014:IPR013656; KEGG: mem:Memar_1158 putative PAS/PAC sensor protein; PFAM: PAS fold-4 domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: C1TPJ4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 0.998
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
Server load: low (20%) [HD]