node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apau_0923 | Apau_2253 | Apau_0923 | Apau_2253 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dtu:Dtur_0614 queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: C1TQH0 PreQ(0) biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | 0.436 |
Apau_0923 | folE2 | Apau_0923 | Apau_0924 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dtu:Dtur_0614 queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: C1TQH0 PreQ(0) biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.991 |
Apau_1006 | Apau_1270 | Apau_1006 | Apau_1270 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 0.865 |
Apau_1006 | Apau_1689 | Apau_1006 | Apau_1689 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.485 |
Apau_1006 | Apau_2253 | Apau_1006 | Apau_2253 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | 0.439 |
Apau_1006 | folE2 | Apau_1006 | Apau_0924 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.834 |
Apau_1006 | ribBA | Apau_1006 | Apau_1356 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.926 |
Apau_1270 | Apau_1006 | Apau_1270 | Apau_1006 | COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | 0.865 |
Apau_1270 | Apau_1689 | Apau_1270 | Apau_1689 | COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.875 |
Apau_1270 | Apau_2253 | Apau_1270 | Apau_2253 | COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | 0.866 |
Apau_1270 | folE2 | Apau_1270 | Apau_0924 | COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.858 |
Apau_1689 | Apau_1006 | Apau_1689 | Apau_1006 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | 0.485 |
Apau_1689 | Apau_1270 | Apau_1689 | Apau_1270 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | COGs: COG0469 Pyruvate kinase; InterProIPR015813:IPR015795:IPR008279:IPR011037:IPR 015794:IPR015793:IPR001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: D1B9W3 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 0.875 |
Apau_1689 | Apau_2253 | Apau_1689 | Apau_2253 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | 0.427 |
Apau_1689 | moaA | Apau_1689 | Apau_1478 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.844 |
Apau_1689 | ribBA | Apau_1689 | Apau_1356 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.876 |
Apau_2252 | Apau_2253 | Apau_2252 | Apau_2253 | KEGG: gym:GYMC10_1695 hypothetical protein; SPTR: C6IZB6 Putative uncharacterized protein. | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | 0.483 |
Apau_2252 | Apau_2254 | Apau_2252 | Apau_2254 | KEGG: gym:GYMC10_1695 hypothetical protein; SPTR: C6IZB6 Putative uncharacterized protein. | Hypothetical protein; KEGG: app:CAP2UW1_0555 TRAP dicarboxylate transporter, DctM subunit; SPTR: C1I6J7 Predicted protein. | 0.448 |
Apau_2253 | Apau_0923 | Apau_2253 | Apau_0923 | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dtu:Dtur_0614 queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: C1TQH0 PreQ(0) biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.436 |
Apau_2253 | Apau_1006 | Apau_2253 | Apau_1006 | KEGG: kra:Krad_3336 protein of unknown function DUF34; SPTR: C2G1Q0 Protein of hypothetical function DUF34; PFAM: NIF3 (NGG1p interacting factor 3). | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tai:Taci_0618 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: D1B9A1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] | 0.439 |