STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Apau_2358Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR011146:IPR001310:IPR011151; KEGG: tai:Taci_1725 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: D1B7E8 Histidine triad (HIT) protein; PFAM: HIT domain. (168 aa)    
Predicted Functional Partners:
Apau_2359
Protein of unknown function UPF0029; COGs: COG1739 conserved hypothetical protein; InterPro IPR020568:IPR001498; KEGG: tai:Taci_1726 protein of unknown function UPF0029; PFAM: protein of unknown function UPF0029; SPTR: D1B7E9 Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; TIGRFAM: uncharacterized protein, YigZ family.
       0.825
Apau_1663
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014021:IPR001650:IPR006935:IPR014001; KEGG: hoh:Hoch_0896 type III restriction protein res subunit; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: C1TKV6 DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
    
  0.791
Apau_2357
Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tai:Taci_1724 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: D1B7E7 ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
       0.775
Apau_2356
COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: tai:Taci_1723 cobyrinic acid ac-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: D1B7E6 Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
       0.773
thrS
Ser-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR002320:IPR004095:IPR012947:IPR002314:IPR 004154:IPR018163:IPR012676:IPR018158:IPR006195; KEGG: tai:Taci_0723 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; TGS domain protein; Anticodon-binding domain protein; SPTR: D1B9K3 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-t [...]
    
 0.753
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.725
Apau_2360
COGs: COG1866 Phosphoenolpyruvate carboxykinase (ATP); InterPro IPR001272; KEGG: cpo:COPRO5265_0282 phosphoenolpyruvate carboxykinase; PFAM: phosphoenolpyruvate carboxykinase (ATP); PRIAM: Phosphoenolpyruvate carboxykinase (ATP); SPTR: B5Y7A2 Phosphoenolpyruvate carboxykinase; PFAM: Phosphoenolpyruvate carboxykinase.
       0.705
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
  0.661
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.660
Apau_0757
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR002869:IPR009014:IPR 002880:IPR019752:IPR019456:IPR001450:IPR011766:IPR017900:I PR015941; KEGG: tai:Taci_1436 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D1B6M5 Pyruvate [...]
   
   0.649
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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