STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apau_2377COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: tai:Taci_1734 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: D1B7F7 Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa)    
Predicted Functional Partners:
Apau_2376
COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR018357:IPR001451; KEGG: tai:Taci_1733 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: D1B7F6 Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
 
 0.999
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR009080:IPR014729:IPR015803:IPR015273:IPR 002308; KEGG: tai:Taci_1012 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: D1B5F3 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.952
Apau_0225
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase.
    
 0.917
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.885
Apau_1921
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterProIPR015424:IPR000277:IPR015421:IPR015422:IPR 006235; KEGG: tai:Taci_1506 O-acetylhomoserineaminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: O-acetylhomoserine aminocarboxypropyltransferase; SPTR: D1B6T7 O-acetylhomoserineaminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 
 0.880
Apau_0913
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: tai:Taci_1275 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: D1B665 Rhodanese domain protein; manually curated; PFAM: Rhodanese-like domain.
  
 
 0.874
Apau_0767
Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR015424:IPR004839:IPR015421; KEGG: tai:Taci_1423 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: D1B6L2 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
    
 0.869
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.866
Apau_0530
MoaD family protein; InterPro IPR012675:IPR016155:IPR010038:IPR003749; KEGG: tai:Taci_0475 MoaD family protein; PFAM: thiamineS protein; SPTR: D1B8V8 MoaD family protein; TIGRFAM: MoaD family protein; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
  
 0.861
Apau_1165
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR015424:IPR001176:IPR015421:IPR 004838; KEGG: tai:Taci_0746 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: D1B9M6 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
    
 0.853
Your Current Organism:
Aminomonas paucivorans
NCBI taxonomy Id: 584708
Other names: A. paucivorans DSM 12260, Aminomonas paucivorans DSM 12260, Aminomonas paucivorans str. DSM 12260, Aminomonas paucivorans strain DSM 12260
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