node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apau_0225 | Apau_0240 | Apau_0225 | Apau_0240 | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR009737:IPR011538:IPR019554:IPR019575:IPR 001450:IPR017900:IPR001949:IPR012336:IPR017896:IPR012335; KEGG: tte:TTE0893 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: C1TS [...] | 0.916 |
Apau_0225 | Apau_0630 | Apau_0225 | Apau_0630 | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | 0.402 |
Apau_0225 | Apau_1810 | Apau_0225 | Apau_1810 | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | Methyltransferase type 11; COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: cje:Cj1325 putative methyltransferase; PFAM: Methyltransferase type 11; SPTR: Q0P8T2 Putative methyltransferase; PFAM: Methyltransferase domain. | 0.619 |
Apau_0225 | Apau_2409 | Apau_0225 | Apau_2409 | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tai:Taci_0499 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: D1B8Y2 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.614 |
Apau_0225 | bioB | Apau_0225 | Apau_0331 | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.402 |
Apau_0234 | Apau_0240 | Apau_0234 | Apau_0240 | Molybdopterin oxidoreductase Fe4S4 region; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR001450:IPR006963:IPR 006656:IPR017900:IPR006655:IPR000283:IPR017896; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; SPTR: A0LP28 Formate dehydrogenase, alpha subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreducta [...] | NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR009737:IPR011538:IPR019554:IPR019575:IPR 001450:IPR017900:IPR001949:IPR012336:IPR017896:IPR012335; KEGG: tte:TTE0893 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: C1TS [...] | 0.997 |
Apau_0234 | Apau_2409 | Apau_0234 | Apau_2409 | Molybdopterin oxidoreductase Fe4S4 region; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR001450:IPR006963:IPR 006656:IPR017900:IPR006655:IPR000283:IPR017896; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; SPTR: A0LP28 Formate dehydrogenase, alpha subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreducta [...] | Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tai:Taci_0499 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: D1B8Y2 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.564 |
Apau_0240 | Apau_0225 | Apau_0240 | Apau_0225 | NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR009737:IPR011538:IPR019554:IPR019575:IPR 001450:IPR017900:IPR001949:IPR012336:IPR017896:IPR012335; KEGG: tte:TTE0893 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: C1TS [...] | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.916 |
Apau_0240 | Apau_0234 | Apau_0240 | Apau_0234 | NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR009737:IPR011538:IPR019554:IPR019575:IPR 001450:IPR017900:IPR001949:IPR012336:IPR017896:IPR012335; KEGG: tte:TTE0893 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: C1TS [...] | Molybdopterin oxidoreductase Fe4S4 region; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR001450:IPR006963:IPR 006656:IPR017900:IPR006655:IPR000283:IPR017896; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; SPTR: A0LP28 Formate dehydrogenase, alpha subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreducta [...] | 0.997 |
Apau_0240 | Apau_2409 | Apau_0240 | Apau_2409 | NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR009737:IPR011538:IPR019554:IPR019575:IPR 001450:IPR017900:IPR001949:IPR012336:IPR017896:IPR012335; KEGG: tte:TTE0893 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: C1TS [...] | Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tai:Taci_0499 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: D1B8Y2 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.697 |
Apau_0427 | Apau_0630 | Apau_0427 | Apau_0630 | 2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterProIPR015421:IPR001917:IPR015424:IPR010962:IPR 004839; KEGG: tai:Taci_1652 pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: D1B775 Pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative. | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | 0.854 |
Apau_0427 | Apau_1810 | Apau_0427 | Apau_1810 | 2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterProIPR015421:IPR001917:IPR015424:IPR010962:IPR 004839; KEGG: tai:Taci_1652 pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: D1B775 Pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative. | Methyltransferase type 11; COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: cje:Cj1325 putative methyltransferase; PFAM: Methyltransferase type 11; SPTR: Q0P8T2 Putative methyltransferase; PFAM: Methyltransferase domain. | 0.482 |
Apau_0427 | Apau_2409 | Apau_0427 | Apau_2409 | 2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterProIPR015421:IPR001917:IPR015424:IPR010962:IPR 004839; KEGG: tai:Taci_1652 pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: D1B775 Pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative. | Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tai:Taci_0499 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: D1B8Y2 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.510 |
Apau_0427 | bioB | Apau_0427 | Apau_0331 | 2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterProIPR015421:IPR001917:IPR015424:IPR010962:IPR 004839; KEGG: tai:Taci_1652 pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: D1B775 Pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.915 |
Apau_0427 | bioD | Apau_0427 | Apau_0332 | 2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterProIPR015421:IPR001917:IPR015424:IPR010962:IPR 004839; KEGG: tai:Taci_1652 pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: D1B775 Pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.964 |
Apau_0630 | Apau_0225 | Apau_0630 | Apau_0225 | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 011005; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: D1B7X8 Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.402 |
Apau_0630 | Apau_0427 | Apau_0630 | Apau_0427 | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | 2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterProIPR015421:IPR001917:IPR015424:IPR010962:IPR 004839; KEGG: tai:Taci_1652 pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: D1B775 Pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative. | 0.854 |
Apau_0630 | Apau_2409 | Apau_0630 | Apau_2409 | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tai:Taci_0499 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: D1B8Y2 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.500 |
Apau_0630 | bioB | Apau_0630 | Apau_0331 | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.867 |
Apau_0630 | bioD | Apau_0630 | Apau_0332 | Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterProIPR006638:IPR005244:IPR007197:IPR010722:IPR 013785; KEGG: dat:HRM2_01530 BioB1; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; SPTR: C1TNR1 Biotin synthase-like enzyme; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.984 |