STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sufSCysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (412 aa)    
Predicted Functional Partners:
sufC
sufC: FeS assembly ATPase SufC.
 
  
 0.989
sufD
sufD: FeS assembly protein SufD.
 
 
 0.986
sufB
sufB: FeS assembly protein SufB.
 
 
 0.978
nifU
nifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.953
trxB
TRX_reduct: thioredoxin-disulfide reductase.
 
 
 0.920
sufE
Cysteine desulfuration protein sufE.
 
 0.912
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.910
metB
O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase.
     
  0.900
csdE
feS_syn_CsdE: cysteine desulfurase, sulfur acceptor subunit CsdE.
 
 0.802
sufA
Protein sufA; Belongs to the HesB/IscA family.
 
 
 0.795
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.