hicB protein (Proteus vulgaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

hicB

Hypothetical protein. (144 aa)

Predicted Functional Partners:

prtA-2

0.655

hpmA

0.645

yjcF

0.640

DR95_2847

0.636

DR95_1521

0.585

qseG

0.578

DR95_1180

0.570

DR95_3673

0.567

nlpE

0.544

DR95_2846

0.536

Your Current Organism:

Proteus vulgaris

NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR95_1180	DR95_3673	DR95_1180	DR95_3673	Hypothetical protein.	Bacterial Ig-like domain family protein.	0.500
DR95_1180	hicB	DR95_1180	DR95_1107	Hypothetical protein.	Hypothetical protein.	0.570
DR95_1180	nlpE	DR95_1180	DR95_2506	Hypothetical protein.	nlpE N-terminal domain protein.	0.692
DR95_1180	qseG	DR95_1180	DR95_77	Hypothetical protein.	yfhG lipofamily protein.	0.720
DR95_1521	DR95_2847	DR95_1521	DR95_2847	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	Autotransporter beta-domain protein.	0.610
DR95_1521	DR95_3673	DR95_1521	DR95_3673	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	Bacterial Ig-like domain family protein.	0.761
DR95_1521	hicB	DR95_1521	DR95_1107	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	Hypothetical protein.	0.585
DR95_1521	prtA-2	DR95_1521	DR95_1654	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	Secreted protease A.	0.441
DR95_1521	qseG	DR95_1521	DR95_77	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	yfhG lipofamily protein.	0.551
DR95_1521	yjcF	DR95_1521	DR95_800	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	Acetyltransferase family protein.	0.434
DR95_2846	DR95_2847	DR95_2846	DR95_2847	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	Autotransporter beta-domain protein.	0.943
DR95_2846	DR95_3673	DR95_2846	DR95_3673	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	Bacterial Ig-like domain family protein.	0.461
DR95_2846	hicB	DR95_2846	DR95_1107	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	Hypothetical protein.	0.536
DR95_2846	hpmA	DR95_2846	DR95_2910	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	Hemolysin.	0.766
DR95_2846	nlpE	DR95_2846	DR95_2506	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	nlpE N-terminal domain protein.	0.481
DR95_2846	prtA-2	DR95_2846	DR95_1654	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	Secreted protease A.	0.460
DR95_2846	qseG	DR95_2846	DR95_77	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	yfhG lipofamily protein.	0.408
DR95_2846	yjcF	DR95_2846	DR95_800	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	Acetyltransferase family protein.	0.434
DR95_2847	DR95_1521	DR95_2847	DR95_1521	Autotransporter beta-domain protein.	Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein.	0.610
DR95_2847	DR95_2846	DR95_2847	DR95_2846	Autotransporter beta-domain protein.	Chondroitin ABC endolyase 1; Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides. Is not active against keratan sulfate, heparan sulfate, and heparin. Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).	0.943

page 1 of 5

Server load: high (88%) [HD]

Permalink

Network

Neighborhood

Textmining

Co-occurrence

Experiments

Co-expression

Databases

Fusion

© STRING Consortium 2026

Credits

Access

Info

About