Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)    
Predicted Functional Partners:
crr
Glucose-specific phosphotransferase enzyme IIA component.
 
 0.999
ptsH
Phosphocarrier protein HPr.
 
 0.999
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component.
 
 0.928
ptsO
Phosphocarrier protein NPr.
 
 
 0.926
bglF
PTS system beta-glucoside-specific EIIBCA component.
 
 
 0.909
dhaM
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM.
 
 
0.857
ptsN
nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.817
cyaA
Adenylate cyclase, class-I family protein; Belongs to the adenylyl cyclase class-1 family.
      
 0.649
pitA
Low-affinity inorganic phosphate transporter 1.
      
 0.627
uhpA
Bacterial regulatory s, luxR family protein.
    
 
 0.588
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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