STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ipdCThiamine pyrophosphate enzyme, central domain protein. (549 aa)    
Predicted Functional Partners:
gltC_2
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
       0.524
phoR
phoR_proteo: phosphate regulon sensor kinase PhoR.
      
 0.491
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
      
 0.491
tolC_2
type_I_sec_TolC: type I secretion outer membrane, TolC family protein.
      
 0.478
prsD
type_I_sec_PrtD: type I secretion system ATPase family protein.
 
    
 0.472
prsE
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
      
 0.472
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.464
alsS
Acolac_catab: acetolactate synthase, catabolic; Belongs to the TPP enzyme family.
  
   
 0.463
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
 
   
 0.445
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
   
  
 0.440
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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