Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBTRX_reduct: thioredoxin-disulfide reductase. (319 aa)    
Predicted Functional Partners:
trxA
Thioredoxin: thioredoxin; Belongs to the thioredoxin family.
 
 0.996
sufS
Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 
  0.921
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
     
 0.915
megL
Met_gam_lyase: methionine gamma-lyase.
   
 
 0.903
mdeA_1
cys/Met metabolism PLP-dependent enzyme family protein.
   
 
 0.903
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.839
ykuV
ahpC/TSA family protein.
  
 
 0.835
trxA_1
Hypothetical protein.
  
 
 0.750
tsaA_1
Hypothetical protein; C-terminal domain of 1-Cys peroxiredoxin family protein.
  
 
 0.738
DR95_3139
Hypothetical protein.
  
 
 0.686
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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