Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
emrA_2RND_mfp: efflux transporter, RND family, MFP subunit. (328 aa)    
Predicted Functional Partners:
ccmA-2
ccmA: heme ABC exporter, ATP-binding protein CcmA.
 
  
 0.974
ybhS
Inner membrane transport permease ybhS.
 
  
 0.961
ybhR
Inner membrane transport permease ybhR.
 
  
 0.956
nicS
Bacterial regulatory s, tetR family protein.
 
  
 0.868
macB
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.751
yhhJ
Inner membrane transport permease yhhJ.
 
  
 0.685
tolC
Outer membrane protein tolC.
  
 
 0.585
DR95_3238
ABC-2 type transporter family protein.
 
    0.495
ccmA-5
ccmA: heme ABC exporter, ATP-binding protein CcmA.
 
  
 0.492
mdtA_1
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.483
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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