Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prtA-2Secreted protease A. (466 aa)    
Predicted Functional Partners:
prsD
type_I_sec_PrtD: type I secretion system ATPase family protein.
 
 
 0.873
tolC_2
type_I_sec_TolC: type I secretion outer membrane, TolC family protein.
 
  
 0.853
prsE
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
 
  
 0.828
shlB
Hemolysin transporter protein shlB.
  
  
 0.717
DR95_2431
Autotransporter beta-domain protein.
 
  
 0.687
hpmA
Hemolysin.
 
  
 0.676
DR95_2847
Autotransporter beta-domain protein.
  
    0.671
hicB
Hypothetical protein.
  
   
 0.655
mrkD
Fimbrial family protein.
  
    0.643
DR95_3673
Bacterial Ig-like domain family protein.
 
    0.639
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
Server load: medium (44%) [HD]
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