tolC_2 protein (Proteus vulgaris) - STRING interaction network

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Score

tolC_2

type_I_sec_TolC: type I secretion outer membrane, TolC family protein. (450 aa)

Predicted Functional Partners:

prsE

0.965

prsD

0.933

prtA-2

0.853

mdtA_2

0.839

mdtA_1

0.813

macA

0.789

macB

0.728

DR95_1903

0.722

emrA_1

0.711

tolC

0.654

Your Current Organism:

Proteus vulgaris

NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR95_1903	tolC_2	DR95_1903	DR95_1657	rTX-family protein.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.722
emrA_1	macB	DR95_1637	DR95_1424	8a0101: efflux pump membrane family protein.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.708
emrA_1	mdtA_1	DR95_1637	DR95_456	8a0101: efflux pump membrane family protein.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.466
emrA_1	tolC	DR95_1637	DR95_2423	8a0101: efflux pump membrane family protein.	Outer membrane protein tolC.	0.748
emrA_1	tolC_2	DR95_1637	DR95_1657	8a0101: efflux pump membrane family protein.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.711
macA	macB	DR95_1425	DR95_1424	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.998
macA	mdtA_1	DR95_1425	DR95_456	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.585
macA	mdtA_2	DR95_1425	DR95_2212	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.618
macA	tolC	DR95_1425	DR95_2423	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein tolC.	0.876
macA	tolC_2	DR95_1425	DR95_1657	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.789
macB	emrA_1	DR95_1424	DR95_1637	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	8a0101: efflux pump membrane family protein.	0.708
macB	macA	DR95_1424	DR95_1425	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.998
macB	mdtA_1	DR95_1424	DR95_456	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.925
macB	mdtA_2	DR95_1424	DR95_2212	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.925
macB	prsE	DR95_1424	DR95_1656	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	0.707
macB	tolC	DR95_1424	DR95_2423	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Outer membrane protein tolC.	0.837
macB	tolC_2	DR95_1424	DR95_1657	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.728
mdtA_1	emrA_1	DR95_456	DR95_1637	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	8a0101: efflux pump membrane family protein.	0.466
mdtA_1	macA	DR95_456	DR95_1425	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide-specific efflux protein macA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.585
mdtA_1	macB	DR95_456	DR95_1424	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.925

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