tolC_2 protein (Proteus vulgaris) - STRING interaction network

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Score

tolC_2

type_I_sec_TolC: type I secretion outer membrane, TolC family protein. (450 aa)

Predicted Functional Partners:

prsE

0.970

prsD

0.937

macB

0.888

prtA-2

0.812

DR95_1903

0.702

hlyD

0.657

mdtA_2

0.600

DR95_3170

0.595

prtA

0.593

DR95_3673

0.591

Your Current Organism:

Proteus vulgaris

NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR95_1903	DR95_3673	DR95_1903	DR95_3673	rTX-family protein.	Bacterial Ig-like domain family protein.	0.789
DR95_1903	tolC_2	DR95_1903	DR95_1657	rTX-family protein.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.702
DR95_3170	macB	DR95_3170	DR95_1424	hlyD secretion family protein.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.760
DR95_3170	mdtA_2	DR95_3170	DR95_2212	hlyD secretion family protein.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.419
DR95_3170	tolC_2	DR95_3170	DR95_1657	hlyD secretion family protein.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.595
DR95_3673	DR95_1903	DR95_3673	DR95_1903	Bacterial Ig-like domain family protein.	rTX-family protein.	0.789
DR95_3673	prtA-2	DR95_3673	DR95_1654	Bacterial Ig-like domain family protein.	Secreted protease A.	0.638
DR95_3673	tolC_2	DR95_3673	DR95_1657	Bacterial Ig-like domain family protein.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.591
hlyD	macB	DR95_2936	DR95_1424	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.760
hlyD	prsD	DR95_2936	DR95_1655	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	type_I_sec_PrtD: type I secretion system ATPase family protein.	0.677
hlyD	prtA	DR95_2936	DR95_1653	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	Secreted protease A.	0.727
hlyD	prtA-2	DR95_2936	DR95_1654	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	Secreted protease A.	0.424
hlyD	tolC_2	DR95_2936	DR95_1657	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.657
macB	DR95_3170	DR95_1424	DR95_3170	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	hlyD secretion family protein.	0.760
macB	hlyD	DR95_1424	DR95_2936	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	0.760
macB	mdtA_2	DR95_1424	DR95_2212	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.983
macB	prsE	DR95_1424	DR95_1656	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	type_I_hlyD: type I secretion membrane fusion, HlyD family protein.	0.760
macB	tolC_2	DR95_1424	DR95_1657	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	type_I_sec_TolC: type I secretion outer membrane, TolC family protein.	0.888
mdtA_2	DR95_3170	DR95_2212	DR95_3170	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	hlyD secretion family protein.	0.419
mdtA_2	macB	DR95_2212	DR95_1424	RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.983

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