STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btuFVitamin B12-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (275 aa)    
Predicted Functional Partners:
btuC
fecCD transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 
 0.923
hmuU_3
ABC 3 transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.896
DR95_2244
ABC 3 transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.882
hmuU_2
fecCD transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.864
fhuB
ABC 3 transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.807
fhuC_1
ABC transporter family protein.
 
 
 0.790
DR95_2243
ABC transporter family protein.
 
 
 0.779
yusV
ABC transporter family protein.
 
 
 0.750
hmuV
Hemin import ATP-binding protein HmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
    0.702
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]
  
  
 0.606
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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