Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
liaSHistidine kinase family protein. (518 aa)    
Predicted Functional Partners:
uhpA
Bacterial regulatory s, luxR family protein.
 
 0.994
degU
Bacterial regulatory s, luxR family protein.
 
 
 0.777
uvrY
Response regulator.
 
 
 0.764
narL
Bacterial regulatory s, luxR family protein.
 
 
 0.755
rcsB
Capsular synthesis regulator component B; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
 
 
 0.742
fbpA
Hypothetical protein.
 
     0.614
uhpC
Regulatory protein uhpC.
  
    0.581
cysT_2
Binding--dependent transport system inner membrane component family protein.
 
     0.562
ugpC_2
ABC transporter family protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
 
     0.466
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
       0.430
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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