Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
phoRphoR_proteo: phosphate regulon sensor kinase PhoR. (432 aa)    
Predicted Functional Partners:
phoB
phoB: phosphate regulon transcriptional regulatory protein PhoB.
 
 0.998
cheY
Chemotaxis protein CheY.
 
 
 0.885
ompR
Transcriptional regulatory protein ompR.
 
 
 0.831
arcB
Aerobic respiration control sensor protein ArcB.
 
 
0.796
phoP
Transcriptional regulatory protein phoP.
 
 
 0.777
arcA
Response regulator.
 
 
 0.737
baeR
Hypothetical protein; Transcriptional regulatory, C terminal family protein.
 
 
 0.726
phoU
Phosphate transport system regulatory protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.
 
  
 0.711
cpxR
Transcriptional regulatory protein CpxR.
 
 
 0.682
ttrS
His Kinase A domain protein.
 
 
 0.662
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
Server load: medium (50%) [HD]