Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DR95_20654Fe-4S dicluster domain protein. (185 aa)    
Predicted Functional Partners:
hyfG
Hydrogenase-4 component G.
 
 
 0.919
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.771
DR95_1848
Hypothetical protein; Oxidoreductase with an extremely broad substrate specificity that can reduce reversibly 2-oxocarboxylates to (2R)- hydroxycarboxylates.
 
 
 
 0.639
nuoG
NADH dehydrogenase (quinone), G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
  
   0.584
hypC-2
hypC_hupF: hydrogenase assembly chaperone HypC/HupF; Belongs to the HupF/HypC family.
       0.579
dmsA-2
Anaerobic dimethyl sulfoxide reductase chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.548
fdxH
Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
     0.542
fdhF_2
Molybdopterin oxidoreductase Fe4S4 domain protein.
 
 
 0.520
DR95_2566
Fdh-alpha: formate dehydrogenase, alpha subunit.
 
 
 0.510
hycG
NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.508
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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