STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prtA-3Secreted protease A. (575 aa)    
Predicted Functional Partners:
prsE
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
 
  
 0.772
prsD
type_I_sec_PrtD: type I secretion system ATPase family protein.
 
 
 0.768
hlyD
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
 
  
 0.747
hlyB
Alpha-hemolysin translocation ATP-binding protein HlyB.
 
  
 0.658
apxIB
ABC transporter family protein.
 
  
 0.656
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
      
 0.565
zapE
Hypothetical protein; Reduces the stability of FtsZ polymers in the presence of ATP.
      
 0.545
DR95_3670
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
  
     0.540
menH
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
 
  
 0.529
DR95_2431
Autotransporter beta-domain protein.
 
  
 0.511
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.