Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cirA_2tonB dependent receptor family protein. (648 aa)    
Predicted Functional Partners:
tonB
Protein tonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.870
DR95_2245
Periplasmic binding family protein.
 
  
 0.830
DR95_2242
Methyltransferase domain protein.
 
     0.766
DR95_2243
ABC transporter family protein.
 
  
 0.683
DR95_245
Hypothetical protein.
  
     0.676
nadC
Hypothetical protein; Quinolinate phosphoribosyl transferase, N-terminal domain protein; Belongs to the NadC/ModD family.
 
  
 0.672
DR95_2244
ABC 3 transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.661
DR95_1849
Putative oxidoreductase.
  
     0.637
DR95_3137
Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.627
DR95_1915
Hypothetical protein; tonB_Cterm: TonB family C-terminal domain protein.
 
 
 0.607
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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