STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
caiBCarnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. (406 aa)    
Predicted Functional Partners:
caiA
crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family.
 
 
 0.985
caiD
carnitinyl-CoA dehydratase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
 
 
 0.947
lcfB_2
AMP-binding enzyme family protein; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine.
 
   
 0.913
caiT
L-carnitine/gamma-butyrobetaine antiporter; Belongs to the BCCT transporter (TC 2.A.15) family.
 
   
 0.829
etfB_2
Electron transfer flavodomain protein; Required for anaerobic carnitine reduction. May bring reductant to CaiA.
 
 
   0.737
etfA_2
Electron transfer flavodomain protein; Required for anaerobic carnitine reduction. May bring reductant to CaiA.
 
   
 0.716
etfB_1
Electron transfer flavodomain protein.
 
 
   0.703
aes
Acetyl esterase.
 
    0.701
fixX_1
Putative ferredoxin-like protein fixX; Could be a 3Fe-4S cluster-containing protein.
 
     0.685
DR95_2291
Putative 4Fe-4S ferredoxin-type oxidoreductase subunit; Could be a 3Fe-4S cluster-containing protein.
 
     0.660
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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